Abstract | INTRODUCTION: PURPOSE AND METHODS: This survey aimed to assess physicians' feelings towards effectiveness, tolerability and clinical impact of generic substitution of antiepileptic drugs on their patients. A questionnaire was sent to all French private neurologists and hospital specialists in epilepsy. Their responses were recorded from December 2005 to March 2006. RESULTS: DISCUSSION: Neurologists' reluctance with prescribing generic AEDs may be explained by several different facts: no controlled study about the safety and efficacy of generic AEDs as compared with brand name drugs, substitutions by pharmacists without their agreement, lack of medical information about generic AEDs, symbolic dimension of the treatment, and, most of all, the fear of breakthrough seizures in patients good controlled. CONCLUSION:
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Authors | A Biraben, B De Toffol, F Semah, T Rouaud |
Journal | Revue neurologique
(Rev Neurol (Paris))
Vol. 163
Issue 4
Pg. 455-61
(Apr 2007)
ISSN: 0035-3787 [Print] France |
Vernacular Title | Utilisation des médicaments génériques des anti-épileptiques en France: résultats d'une enquête auprès des neurologues et revue de la littérature. |
PMID | 17452947
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Anticonvulsants
- Drugs, Generic
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Topics |
- Anticonvulsants
(adverse effects, therapeutic use)
- Drug Utilization
- Drugs, Generic
(adverse effects, therapeutic use)
- Epilepsy
(drug therapy)
- France
(epidemiology)
- Neurology
(trends)
- Pharmacists
- Surveys and Questionnaires
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