Mycobacterium fortuitum-induced persistent parotitis: successful therapy with clarithromycin and ciprofloxacin.

Abstract

BACKGROUND:

Parotitis caused by nontuberculous mycobacteria, a very rare disease entity, has never been reported to be caused by Mycobacterium fortuitum (M. fortuitum) in the literature.

METHODS AND RESULTS:

An 8-year-old girl was seen with painful swelling of the right parotid gland despite antibiotic treatment of more than 1 month. Elevated serum amylase activity and diffuse contrast-enhanced CT of the parotid gland confirmed the diagnosis of parotitis. Histopathological study of specimens taken from the right parotid tail mass showed granulomatous inflammation with acid-fast positive bacilli; culture later confirmed M. fortuitum. After administration of clarithromycin and ciprofloxacin for 9 consecutive months, the parotitis and parotid tail mass were completely resolved at follow-up examination.

CONCLUSION:

To our knowledge, this is the first case report of parotitis caused by M. fortuitum and its successful medical treatment.

• Authors: Chien-Cheng Chen, Shiou-Yi Chen, Yun-Sung Chen, Cheng-Yu Lo, Po-Wen Cheng
• Journal: Head & neck (Head Neck) Vol. 29 Issue 11 Pg. 1061-4 (Nov 2007) ISSN: 1043-3074 [Print] United States
• PMID: 17427970 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Ciprofloxacin
• Clarithromycin

Topics

• Anti-Bacterial Agents (therapeutic use)
• Child
• Ciprofloxacin (therapeutic use)
• Clarithromycin (therapeutic use)
• Female
• Humans
• Mycobacterium Infections, Nontuberculous (drug therapy)
• Mycobacterium fortuitum
• Parotitis (drug therapy, microbiology)