Abstract | OBJECTIVE: Few effective treatments are available for severe forms of bulimia nervosa, which are accompanied by malnutrition, anxiety, and depressive mood. We previously showed in an open study that nasogastric tube feeding (TF) reduced binges and purging in patients with anorexia nervosa. METHODS: This prospective randomized trial compared bulimia patients in two treatment groups: one group received TF at home, together with psychotherapy, nutritional counseling and a support group while the control group received only psychotherapy, nutritional counseling, and a support group. Patients in the first group underwent TF for 8 weeks (exclusively for 10 days and associated with meals thereafter). Assessment was based on clinical examination, laboratory results, and a variety of questionnaires (our in-house instrument for measuring binge and vomiting episodes, eating disorder inventory, Beck's depression inventory and the Hamilton rating scale for anxiety), all performed at the onset of treatment and at 8 days, 8 weeks (i.e., the end of TF), and 3 months after treatment began. RESULTS: Binges and vomiting disappeared faster and more frequently in TF patients than in the control group: 65% versus 29% (p<0.01). Three months later, these remained less frequent in the TF group than among controls (52% versus 33%, p=0.064). Nutritional status, depression, and anxiety improved more among the TF than control subjects (p<0.05). CONCLUSION:
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Authors | Daniel Rigaud, Véronique Brayer, Violaine Biton-Jélic, Vanessa Païs, Hélène Pennacchio, Jean-Marcel Brun |
Journal | Presse medicale (Paris, France : 1983)
(Presse Med)
Vol. 36
Issue 10 Pt 1
Pg. 1354-63
(Oct 2007)
ISSN: 0755-4982 [Print] France |
Vernacular Title | Intérêt de la nutrition entérale par sonde nasogastrique dans la boulimie. Etude contrôlée avec suivi de 3 mois. |
PMID | 17408917
(Publication Type: Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Topics |
- Anxiety
(diagnosis)
- Bulimia
(diagnosis, psychology, therapy)
- Counseling
- Data Interpretation, Statistical
- Depression
(diagnosis)
- Enteral Nutrition
- Follow-Up Studies
- Humans
- Nutritional Status
- Prospective Studies
- Psychotherapy
- Self-Help Groups
- Surveys and Questionnaires
- Time Factors
- Treatment Outcome
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