Abstract | BACKGROUND: Current guidelines for the treatment of hypertension do not provide specific recommendations for obese hypertensive patients. To identify an optimal treatment regimen for obese hypertensive patients, we studied the interactions between a drug-based weight loss approach by sibutramine and different antihypertensive drug regimens. METHODS AND RESULTS: CONCLUSIONS:
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Authors | Jürgen Scholze, Elmar Grimm, Dana Herrmann, Thomas Unger, Ulrich Kintscher |
Journal | Circulation
(Circulation)
Vol. 115
Issue 15
Pg. 1991-8
(Apr 17 2007)
ISSN: 1524-4539 [Electronic] United States |
PMID | 17404163
(Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antihypertensive Agents
- Appetite Depressants
- Cyclobutanes
- Indoles
- Hydrochlorothiazide
- trandolapril
- Verapamil
- Metoprolol
- Ramipril
- Felodipine
- sibutramine
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Topics |
- Adult
- Aged
- Antihypertensive Agents
(therapeutic use)
- Appetite Depressants
(therapeutic use)
- Blood Pressure
(drug effects)
- Body Weight
(drug effects)
- Cyclobutanes
(therapeutic use)
- Double-Blind Method
- Drug Interactions
- Drug Therapy, Combination
- Felodipine
(therapeutic use)
- Female
- Humans
- Hydrochlorothiazide
(therapeutic use)
- Hypertension
(complications, drug therapy, physiopathology)
- Indoles
(therapeutic use)
- Male
- Metoprolol
(analogs & derivatives, therapeutic use)
- Middle Aged
- Obesity
(complications, drug therapy, physiopathology)
- Prospective Studies
- Ramipril
(therapeutic use)
- Treatment Outcome
- Verapamil
(therapeutic use)
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