[A comparison of the value of magnetic resonance tomography and computed tomography in Nelson syndrome patients].

Abstract

The hypophyses of 13 patients with Nelson syndrome following bilateral adrenalectomy were examined by MRI and CT. Diffuse enlargement of the hypophysis was demonstrated in 8 patients by CT and in 9 by MRI. Compared with CT, MRI provides better demonstration of tumour development, such as abnormal convexity of the cranial margin of the hypophysis (MRI 4/13, CT 1/13), displacement of the infundibulum (MRI 4/13, CT 0/13) or optic chiasm (MRI 2/13, CT 0/13). MRI also provides diagnostically important differentiation between scar tissue and recurrence of tumour following hypophysectomy (MRI 1/3, CT 0/3) and more accurate demonstration of infiltration of the cavernous sinus (MRI 4/13, CT 2/13). CT is superior only in showing the floor of the sella. MRI is the method of choice for imaging in cases of Nelson syndrome.

• Authors: W Kersjes, S Allmendinger, H Stiebler, F Christ, A Bockisch, D Klingmüller
• Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin (Rofo) Vol. 156 Issue 2 Pg. 166-71 (Feb 1992) ISSN: 1438-9029 [Print] Germany
• Vernacular Title: Vergleich der Wertigkeit von Magnetresonanztomographie und Computertomographie bei Patienten mit Nelson-Syndrom.
• PMID: 1739777 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Iopamidol

Topics

• Adrenalectomy
• Adult
• Evaluation Studies as Topic
• Female
• Humans
• Hypophysectomy
• Iopamidol
• Magnetic Resonance Imaging (instrumentation, methods)
• Male
• Middle Aged
• Nelson Syndrome (diagnosis)
• Neoplasm Recurrence, Local (diagnosis)
• Pituitary Gland (diagnostic imaging, pathology)
• Pituitary Neoplasms (diagnosis)
• Tomography, X-Ray Computed (methods)