Abstract | INTRODUCTION: METHODS: Eighty-eight subjects aged 1 to 12 years scheduled for strabismus surgery were enrolled in a double-masked randomized control trial. The patients were randomized to one of three groups: Group A received normal saline drops before and after surgery; Group B received normal saline drops before and tetracaine 1% drops after surgery; Group C received tetracaine 1% drops before and after surgery. An observer masked to group assignment assessed each patient in the postanesthesia care unit (PACU) using both a behavior scale and a modified behavioral pain scale. RESULTS: Patients in Group A were found to be in significantly more pain than Groups B or C at 5 minutes after arrival to the PACU (p < 0.013). Using the behavior scale, a significantly greater proportion of patients in Group A were crying or crying and thrashing at 5, 15, and 30 minutes after arrival to the PACU (5 minutes, p < 0.019; 15 minutes, p < 0.041; 30 minutes, p < 0.021). There was no significant difference between groups in total PACU time, PACU vomiting, PACU morphine use, or pain at home. CONCLUSIONS:
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Authors | William Anninger, Brian Forbes, Graham Quinn, Mark S Schreiner |
Journal | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
(J AAPOS)
Vol. 11
Issue 3
Pg. 273-6
(Jun 2007)
ISSN: 1091-8531 [Print] United States |
PMID | 17383912
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anesthetics, Local
- Ophthalmic Solutions
- Tetracaine
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Topics |
- Administration, Topical
- Anesthetics, Local
(administration & dosage)
- Behavioral Symptoms
- Child
- Child, Preschool
- Double-Blind Method
- Female
- Humans
- Infant
- Male
- Oculomotor Muscles
(surgery)
- Ophthalmic Solutions
- Pain, Postoperative
(drug therapy)
- Postoperative Care
- Preoperative Care
- Psychomotor Disorders
(drug therapy)
- Research Design
- Strabismus
(surgery)
- Tetracaine
(administration & dosage)
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