Abstract | PURPOSE: DATA SOURCES: English-language articles were identified through a search of the MEDLINE and Index Medicus databases. Bibliographies of retrieved articles were examined for relevant articles. STUDY SELECTION: Approximately 250 articles were reviewed. Those articles deemed most representative were utilized. Case reports were included to highlight rare, but potentially lethal complications. DATA EXTRACTION: All data were analyzed by one observer. Limitations of the data are discussed. DATA SYNTHESIS: Guidelines for determining the etiology of thyrotoxic crisis are outlined. Criteria for distinguishing critically ill hypothyroid patients from those patients with the euthyroid sick syndrome are given. Therapy for both disorders must be aggressive and multifaceted, and detailed management is indicated. Substernal goiter is almost always benign, but may cause various acute complications, including dyspnea, respiratory failure, superior vena caval syndrome, esophageal varices (downhill), and others. Surgery almost always corrects the problem. Lymphomas present with rapid thyroid enlargement. Recent studies suggest that surgery may assume more of a supportive role, used principally to obtain adequate tissue for histologic classification. CONCLUSIONS:
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Authors | R C Smallridge |
Journal | Critical care medicine
(Crit Care Med)
Vol. 20
Issue 2
Pg. 276-91
(Feb 1992)
ISSN: 0090-3493 [Print] United States |
PMID | 1737461
(Publication Type: Journal Article, Review)
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Topics |
- Airway Obstruction
(etiology)
- Emergencies
- Goiter
(complications)
- Humans
- Hypothyroidism
(diagnosis, therapy)
- Myxedema
(diagnosis, therapy)
- Superior Vena Cava Syndrome
(etiology)
- Thyroid Diseases
(diagnosis, physiopathology, therapy)
- Thyroid Gland
(physiology)
- Thyrotoxicosis
(diagnosis, therapy)
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