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Prevention of blindness in giant cell arteritis by corticosteroid treatment.

Abstract
Ninety-six patients with giant cell arteritis (GCA) seen from 1968 to 1985 were studied with regard to the starting dose of prednisolone and the development of serious ocular complications, which proved to be very few after treatment was started. Those starting on 20 mg of prednisolone or less daily fared at least as well as those starting on higher doses. Analysis of the literature does not support the belief that higher doses provide greater protection from blindness.
AuthorsA B Myles, T Perera, M G Ridley
JournalBritish journal of rheumatology (Br J Rheumatol) Vol. 31 Issue 2 Pg. 103-5 (Feb 1992) ISSN: 0263-7103 [Print] England
PMID1737222 (Publication Type: Journal Article)
Chemical References
  • Prednisolone
Topics
  • Blindness (etiology, prevention & control)
  • Dose-Response Relationship, Drug
  • Giant Cell Arteritis (complications, drug therapy)
  • Humans
  • Prednisolone (administration & dosage, therapeutic use)
  • Prospective Studies
  • Vision Disorders (etiology)

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