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In vivo antitussive potentiality of Lagerstroemia parviflora flower extract using a cough model induced by sulfur dioxide in mice.

Abstract
The methanol extract of the flowers of Lagerstroemia parviflora Roxb (Family: Lythraceae) was investigated for its effect on a cough model induced by sulphur dioxide gas in mice. It exhibited significant antitussive activity when compared with the control in a dose-dependent manner. The extract (100, 200, 300 mg kg(-1)) showed maximum inhibition of cough reflex at 90 min after drug administration and the antitussive activity was comparable to that of codeine phosphate, a standard antitussive agent.
AuthorsAvijit Mazumder, S Bhattacharya, Rupa Mazumder
JournalNatural product research (Nat Prod Res) Vol. 21 Issue 3 Pg. 217-20 (Mar 2007) ISSN: 1478-6419 [Print] England
PMID17365711 (Publication Type: Journal Article)
Chemical References
  • Antitussive Agents
  • Plant Extracts
  • Sulfur Dioxide
Topics
  • Algorithms
  • Animals
  • Antitussive Agents (pharmacology)
  • Cough (chemically induced, drug therapy)
  • Dose-Response Relationship, Drug
  • Flowers (chemistry)
  • Lagerstroemia (chemistry)
  • Mice
  • Plant Extracts (pharmacology)
  • Sulfur Dioxide

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