Abstract |
The methanol extract of the flowers of Lagerstroemia parviflora Roxb (Family: Lythraceae) was investigated for its effect on a cough model induced by sulphur dioxide gas in mice. It exhibited significant antitussive activity when compared with the control in a dose-dependent manner. The extract (100, 200, 300 mg kg(-1)) showed maximum inhibition of cough reflex at 90 min after drug administration and the antitussive activity was comparable to that of codeine phosphate, a standard antitussive agent.
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Authors | Avijit Mazumder, S Bhattacharya, Rupa Mazumder |
Journal | Natural product research
(Nat Prod Res)
Vol. 21
Issue 3
Pg. 217-20
(Mar 2007)
ISSN: 1478-6419 [Print] England |
PMID | 17365711
(Publication Type: Journal Article)
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Chemical References |
- Antitussive Agents
- Plant Extracts
- Sulfur Dioxide
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Topics |
- Algorithms
- Animals
- Antitussive Agents
(pharmacology)
- Cough
(chemically induced, drug therapy)
- Dose-Response Relationship, Drug
- Flowers
(chemistry)
- Lagerstroemia
(chemistry)
- Mice
- Plant Extracts
(pharmacology)
- Sulfur Dioxide
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