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Donepezil in the treatment of musical hallucinations.

Abstract
Musical hallucinations (MH) typically occur among elderly individuals and are associated with hearing impairment. The authors describe a patient with features of typical MH who was successfully treated with donepezil, a cholinesterase inhibitor, as a combination therapy and who has not shown any subsequent cognitive decline for approximately 5 years. The efficacy of donepezil in this patient indicates that age-dependent dysfunction of cholinergic neurons might be related to the development of MH.
AuthorsSatoshi Ukai, Masakiyo Yamamoto, Michio Tanaka, Kazuhiro Shinosaki, Masatoshi Takeda
JournalPsychiatry and clinical neurosciences (Psychiatry Clin Neurosci) Vol. 61 Issue 2 Pg. 190-2 (Apr 2007) ISSN: 1323-1316 [Print] Australia
PMID17362438 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Indans
  • Nootropic Agents
  • Piperidines
  • Donepezil
Topics
  • Aged, 80 and over
  • Donepezil
  • Drug Therapy, Combination
  • Female
  • Hallucinations (drug therapy, psychology)
  • Hearing Disorders (complications)
  • Humans
  • Indans (therapeutic use)
  • Music (psychology)
  • Nootropic Agents (therapeutic use)
  • Piperidines (therapeutic use)

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