Abstract | INTRODUCTION: METHODS: 84 patients with newly exacerbated lumbar radicular pain were randomly al located into two groups. 43 patients under went ESI with 80 mg Depo-Medrol and 41 age- and sex-matched cases received 40 mg Depo-Medrol as the comparison group. The pain in the second week, and every month thereafter was assessed using a visual analogue scale (VAS). RESULTS: Remarkable improvement in one month VAS occurred in 64 cases (75 percent) from both groups. VAS values between 80 mg and 40 mg groups were comparable in the two-week (p-value is 0.827) and three-month (p-value is greater than 0.746) post-injection periods. Slightly better results were shown in patients in the 40 mg group after one month. CONCLUSION: In the case of lumbar radicular pain, ESI with low dose (40 mg) methylprednisolone is as effective as high dose (80 mg) with comparable results and less adverse profile.
|
Authors | M B Owlia, A Salimzadeh, Gh Alishiri, A Haghighi |
Journal | Singapore medical journal
(Singapore Med J)
Vol. 48
Issue 3
Pg. 241-5
(Mar 2007)
ISSN: 0037-5675 [Print] India |
PMID | 17342295
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Anti-Inflammatory Agents
- Glucocorticoids
- Methylprednisolone Acetate
- Methylprednisolone
|
Topics |
- Adult
- Anti-Inflammatory Agents
(administration & dosage)
- Female
- Glucocorticoids
(administration & dosage)
- Humans
- Injections, Epidural
- Male
- Methylprednisolone
(administration & dosage, analogs & derivatives)
- Methylprednisolone Acetate
- Pain Measurement
- Radiculopathy
(drug therapy)
|