A booster vaccination with Mycobacterium bovis BCG does not increase the protective effect of the vaccine against experimental Mycobacterium ulcerans infection in mice.

Abstract	Buruli ulcer, caused by Mycobacterium ulcerans, is a necrotizing skin disease emerging particularly in West Africa. M. bovis BCG vaccine offers only short-term protection against experimental footpad infection of C57BL/6 mice with M. ulcerans, and the duration of this protection cannot be prolonged by a booster vaccination.
Authors	Audrey Tanghe, Pierre-Yves Adnet, Tatiana Gartner, Kris Huygen
Journal	Infection and immunity (Infect Immun) Vol. 75 Issue 5 Pg. 2642-4 (May 2007) ISSN: 0019-9567 [Print] United States
PMID	17325046 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	BCG Vaccine
Topics	Animals BCG Vaccine (administration & dosage, immunology) Disease Models, Animal Foot (microbiology) Humans Immunization, Secondary Mice Mice, Inbred C57BL Mycobacterium Infections, Nontuberculous (microbiology, mortality, prevention & control) Mycobacterium bovis (immunology) Mycobacterium ulcerans (pathogenicity)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!