Reversible endotension associated with excessive warfarin anticoagulation.

Abstract

An aortic aneurysm was successfully treated with an endovascular stent graft, with no evidence of endoleak and documented progressive aortic diameter reduction during the first 23 months. At 29 months, the patient had documented enlargement of the aneurysm sac associated with excessive anticoagulation with warfarin. No evidence of endoleak could be demonstrated with any diagnostic modality. Progressive aneurysm sac diameter regression was documented after reversal of excessive anticoagulation to therapeutic levels (international normalized ratio of 2 to 3). Strict monitoring of coagulation profile in patients after endovascular aneurysm repair requiring anticoagulation with warfarin is recommended to avoid this complication, which to our knowledge has not been previously reported.

• Authors: Vikram S Iyer, Kent S Mackenzie, Marc-Michel Corriveau, Oren K Steinmetz
• Journal: Journal of vascular surgery (J Vasc Surg) Vol. 45 Issue 3 Pg. 600-2 (Mar 2007) ISSN: 0741-5214 [Print] United States
• PMID: 17321347 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anticoagulants
• Warfarin

Topics

• Aged
• Anticoagulants (adverse effects)
• Aortic Aneurysm, Abdominal (blood, pathology, surgery)
• Aortography
• Blood Coagulation (drug effects)
• Blood Vessel Prosthesis Implantation
• Humans
• International Normalized Ratio
• Male
• Stents
• Time Factors
• Tomography, X-Ray Computed
• Treatment Outcome
• Warfarin (adverse effects)