Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.

Abstract

BACKGROUND:

Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease.

CASE:

We report a rare case of gastrinoma that was first diagnosed during pregnancy in which the primary tumor was located in the liver. The ZES was well controlled with Zoton (Lansoprazole) following surgery. The patient had an uneventful pregnancy and delivery without significant complications.

CONCLUSIONS:

The present case suggests that treatment with Zoton for ZES during pregnancy is safe and effective.

• Authors: Amit Mayer, Eyal Sheiner, Gershon Holcberg
• Journal: Archives of gynecology and obstetrics (Arch Gynecol Obstet) Vol. 276 Issue 2 Pg. 171-3 (Aug 2007) ISSN: 0932-0067 [Print] Germany
• PMID: 17318560 (Publication Type: Case Reports, Journal Article)

Chemical References

• 2-Pyridinylmethylsulfinylbenzimidazoles
• Anti-Ulcer Agents
• Gastrins
• Lansoprazole

Topics

• 2-Pyridinylmethylsulfinylbenzimidazoles (therapeutic use)
• Adult
• Anti-Ulcer Agents (therapeutic use)
• Female
• Gastrinoma (complications, drug therapy, pathology, surgery)
• Gastrins (blood)
• Humans
• Infant, Newborn
• Lansoprazole
• Male
• Pregnancy
• Pregnancy Complications, Neoplastic (blood, drug therapy, surgery)
• Pregnancy Outcome
• Zollinger-Ellison Syndrome (blood, complications, drug therapy, surgery)