Abstract | OBJECTIVE: To investigate the expression of microvessel density (MVD) in multistep tissue of gastric carcinoma and CD34 in the multistep tissue of gastric carcinogens. METHODS: RESULTS: The mean MVD was 13 +/- 10 in the specimens of chronic gastritis, 11 +/- 7 in the chronic atrophic gastritis group, 13 +/- 9 in the intestinal metaplasia group, 17 +/- 10 in the dysplasia group, 27 +/- 11 in the gastric carcinoma without lymph node metastases group, and 28 +/- 10 in the gastric carcinoma with lymph node metastases group. There were not significant differences in MVD among the chronic gastritis group, chronic atrophic gastritis group, and intestinal metaplasia group (all P > 0.05), there was a significant difference in MVD between the chronic gastritis group and dysplasia group (P < 0.05). In the specimens of gastric carcinoma, there were no significant difference in MVD between those with and without lymph node metastases (P > 0.05), and between those of high and low differentiation degrees (both P < 0.05). CONCLUSION:
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Authors | Yin-xue Xi, Xin Song, Hui-xin Chen, Ting-sheng Peng, Min-hu Chen |
Journal | Zhonghua yi xue za zhi
(Zhonghua Yi Xue Za Zhi)
Vol. 86
Issue 48
Pg. 3405-8
(Dec 26 2006)
ISSN: 0376-2491 [Print] China |
PMID | 17313853
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Antigens, CD34
(biosynthesis)
- Capillaries
(chemistry, pathology)
- Female
- Gastritis
(metabolism, pathology)
- Humans
- Immunohistochemistry
- Lymphatic Metastasis
- Male
- Middle Aged
- Neoplasm Staging
- Stomach Neoplasms
(blood supply, metabolism, pathology)
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