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[Evaluation on effects of disassembled formulas of Xuefu Zhuyu Decoction for treatment of angina pectoris using Seattle Angina Questionnaire].

AbstractOBJECTIVE:
To evaluate the therapeutic effect of disassembled formulas of Xuefu Zhuyu Decoction (XZD) for treatment of angina pectoris (AP) of coronary heart disease (CHD) using Seattle Angina Questionnaire (SAQ).
METHODS:
One hundred and twenty-three AP patients were randomly assigned to the XZD group, the refined XZD group, the drug-pair group and the placebo group. The therapeutic effect on scores in various aspects, including anginal stability ( I ), anginal attack frequency (II), satisfaction on treatment (II) and cognitive level on disease (IV) of patients was evaluated using SAQ before and after treatment.
RESULTS:
After treatment, improvement was shown on scores of I , II and III in the XZD group, on those of all the four scores in the refined XZD group, on those of scores I and II in the drug-pair group and in the placebo group only on scores of I was improved significantly (P < 0.05 or P < 0.01). The improvement on scores of I in the 3 treated groups was better significantly than that in the placebo group (P < 0.05).
CONCLUSION:
It is feasible to evaluate the therapeutic effect of disassembled formulas of XZD on AP of CHD with SAQ; XZD and its disassembled formulas shows better effects than that of placebo in improving the condition of angina attack.
AuthorsLu Jing, Jie Wang, Ting Wang
JournalZhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 27 Issue 1 Pg. 18-20 (Jan 2007) ISSN: 1003-5370 [Print] China
PMID17302057 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Drugs, Chinese Herbal
  • Xue-Fu-Zhu-Yu decoction
Topics
  • Adult
  • Aged
  • Angina Pectoris (drug therapy, psychology)
  • Drugs, Chinese Herbal (therapeutic use)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Phytotherapy
  • Quality of Life
  • Sickness Impact Profile
  • Surveys and Questionnaires
  • Treatment Outcome

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