Abstract |
A conjugate addition- aldol- dehydration reaction of alpha,beta-unsaturated aldehydes with 2-N-protected amino benzaldehydes has been developed. The process is promoted by (S)- diphenylprolinol TES ether to afford synthetically useful 1,2-dihydroquinolines in high enantioselectivities with good yields. [reaction: see text]
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Authors | Hao Li, Jian Wang, Hexin Xie, Liansuo Zu, Wei Jiang, Eileen N Duesler, Wei Wang |
Journal | Organic letters
(Org Lett)
Vol. 9
Issue 6
Pg. 965-8
(Mar 15 2007)
ISSN: 1523-7060 [Print] United States |
PMID | 17298072
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
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Chemical References |
- Aldehydes
- Amines
- Benzaldehydes
- Pyrrolidines
- Quinolines
- Tromethamine
- Ether
- prolinol
- TES
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Topics |
- Aldehydes
(chemistry)
- Amines
(chemistry)
- Benzaldehydes
(chemistry)
- Dehydration
- Ether
(analogs & derivatives)
- Models, Chemical
- Pyrrolidines
(chemistry)
- Quinolines
(chemical synthesis)
- Stereoisomerism
- Tromethamine
(analogs & derivatives, chemistry)
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