Peritoneal hemorrhage due to a ruptured ovarian cyst in ITP.

Abstract

Immune thrombocytopenic purpura in children rarely causes severe bleeding. The incidence of intracranial hemorrhage is approximately 0.2% to 1.0%, and severe bleeding (defined as persistent epistaxis, melena, menorrhagia, gastrointestinal bleeding, etc, requiring hospitalization or transfusion) occurs in only 5% of patients. Epstein-Barr virus (EBV) associated idiopathic thrombocytopenic purpura (ITP) tends to behave similarly to non-EBV - associated ITP with no increase in hemorrhagic complications and only a small increase in time to remission. Immune thrombocytopenic purpura diagnosed in adolescence is more likely to be chronic then in childhood ITP, but has a higher rate of spontaneous resolution than in adults. However, females in this age group are in their early childbearing years and present a unique set of possible hemorrhagic complications not seen in younger patients. We present the case of an 18-year-old female with EBV-associated ITP, who developed a severe intra-abdominal bleed secondary to a hemorrhagic ovarian cyst.

• Authors: Joel Kaplan, Christine C Bannon, Michael Hulse, Andrew Freiberg
• Journal: Journal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 29 Issue 2 Pg. 117-20 (Feb 2007) ISSN: 1077-4114 [Print] United States
• PMID: 17279009 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Adolescent
• Epstein-Barr Virus Infections (complications)
• Erythrocyte Transfusion (adverse effects)
• Female
• Hemorrhage (etiology, therapy)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Ovarian Cysts (complications, pathology)
• Peritoneum (pathology)
• Purpura, Thrombocytopenic, Idiopathic (complications)
• Respiratory Distress Syndrome (etiology)
• Rupture, Spontaneous (complications)
• Tomography, X-Ray Computed