Abstract | INTRODUCTION: METHODS: Thirty-two female 8-week-old Wistar rats were separated into 4 groups. Two groups (6 rats per group) were controls; they did not undergo orthodontic tooth movement. The other 2 groups (10 rats per group) had orthodontic tooth movement consisting of activated 100-g closing nickel-titanium coils (NiTi 10-000-06, GAC International, Bohemia, NY) connecting the mandibular first molar to the incisors. Fluoridated water (100 ppm) was given ad libitum to 1 control and 1 experimental group. The other 2 groups received deionized water. After 2 weeks, the animals were killed, and the samples were harvested. Resorption craters were scanned with a Micro CT (SkyScan 1072, Aartselaar, Belgium). Software analysis of the scanned samples provided a volumetric measurement of the resorption craters on the mandibular molar cementum surface. RESULTS: Resorption sites were found in the control samples, especially on the distal surfaces; this could be attributed to normal physiological tooth drift. Resorption sites were significantly (P <.05) increased in the groups receiving orthodontic tooth movement. CONCLUSIONS:
Fluoride reduces the size of resorption craters, but the effect is variable and not statistically significant (P >.05).
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Authors | Matthew Foo, Alan Jones, M Ali Darendeliler |
Journal | American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
(Am J Orthod Dentofacial Orthop)
Vol. 131
Issue 1
Pg. 34-43
(Jan 2007)
ISSN: 1097-6752 [Electronic] United States |
PMID | 17208104
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Administration, Oral
- Analysis of Variance
- Animals
- Dental Cementum
(diagnostic imaging, metabolism)
- Female
- Radiographic Image Interpretation, Computer-Assisted
- Random Allocation
- Rats
- Rats, Wistar
- Root Resorption
(etiology, prevention & control)
- Sodium Fluoride
(administration & dosage, pharmacokinetics, therapeutic use)
- Tomography, X-Ray Computed
(methods)
- Tooth Movement Techniques
(adverse effects)
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