Abstract | OBJECTIVES: METHODS: The clinical data of 30 Chinese pancreatoblastoma patients (among them, 1 case was treated by authors, and the other 29 cases were reported in Chinese literature from January 1981 to December 2005) were reviewed and analyzed. RESULTS: Patients with pancreatoblastoma had an age range of 5 months to 42 years. There were 24 children and 6 adult cases, with a male-female ratio of 2:1 (20/10). The tumor size ranged from 2 to 20 cm in diameter. Metastases were found during the operation in 8 cases (26.7%) (among them, 66% with liver invasion and 50% with multiple metastases including spleen, kidney, and bone). Pancreatoduodenectomy was performed in 5 cases (16.7%). Nine cases (30%) received chemotherapy with vincristine, cyclophosphamide, and adriamycin. By immunohistochemistry, the tumors exhibited acinar, endocrine, and ductal differentiation. The mean time of survival was 25.5 months. CONCLUSIONS: These results suggest that the diagnosis of pancreatoblastoma mainly depends on the pathological findings, surgical resection is the most effective way for cure, and adjuvant chemotherapy could be a good palliative method in certain patients.
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Authors | Liping Cao, Daren Liu |
Journal | Pancreas
(Pancreas)
Vol. 34
Issue 1
Pg. 92-5
(Jan 2007)
ISSN: 1536-4828 [Electronic] United States |
PMID | 17198189
(Publication Type: Case Reports, Journal Article, Review)
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Topics |
- Antineoplastic Combined Chemotherapy Protocols
(administration & dosage)
- Child, Preschool
- China
- Combined Modality Therapy
- Female
- Humans
- Male
- Pancreatic Neoplasms
(diagnosis, drug therapy, surgery)
- Pancreaticoduodenectomy
- Survival Rate
- Treatment Outcome
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