Left extended hepatectomy for a metastatic gastrointestinal stromal tumor after a disease-free interval of 17 years: report of a case.

Abstract

Gastrointestinal stromal tumors (GISTs), although rare, are frequently diagnosed with liver metastasis. These metastatic GISTs are poorly responsive to conventional chemotherapy; however, recent studies report improved survival after complete surgical resection of liver metastases. On the other hand, few reports describe the treatment of delayed liver metastasis after resection of a primary GIST. We report the case of a 55-year-old woman found to have liver metastasis from a GIST after a 17-year disease-free interval. The patient underwent a left extended hepatectomy for a complete resection of the metastatic GIST and is alive and well 30 months later. To our knowledge, this is the longest disease-free interval reported in the literature, and emphasizes the importance of considering late metastasis when evaluating patients with a history of GIST. Thus, surgical resection of delayed liver metastasis from a GIST should be considered as primary therapy.

• Authors: Lea Matsuoka, Maria Stapfer, Rod Mateo, Nicolas Jabbour, Win Naing, Rick Selby, Singh Gagandeep
• Journal: Surgery today (Surg Today) Vol. 37 Issue 1 Pg. 70-3 ( 2007) ISSN: 0941-1291 [Print] Japan
• PMID: 17186351 (Publication Type: Case Reports, Journal Article)

Topics

• Female
• Gastrointestinal Stromal Tumors (secondary, surgery)
• Hepatectomy
• Humans
• Jejunal Neoplasms (pathology, surgery)
• Liver Neoplasms (secondary, surgery)
• Middle Aged
• Retroperitoneal Neoplasms (pathology, surgery)
• Time Factors