Abstract | AIM: MATERIAL AND METHODS: Twenty six female renal graft-recipients, aged from 18 to 44 (mean 31 years), who used combined low-dose oral contraceptives after renal transplantation for at least 18 months were enrolled in the study. All patients had stable graft function with mean serum creatinine of 1.3 mg/dl. In 58% of women effective contraception was the mean indication for the therapy, in the remaining group pills were indicated additionally for the development of ovarian cysts and excessive menstrual bleedings. Ethinyl estradiol dose was 20 mug in 73% of cases and 30-35 microg in the remaining group. RESULTS: CONCLUSIONS: Despite the presence of relative contraindications for hormonal drugs (arterial hypertension and deteriorated liver function) in female renal recipients, administration of combined low-dose contraceptive pill should be taken into account as highly effective contraceptive method, that additionally regulates menstrual bleeding patterns, protects from ovarian cysts development and improves life quality of the patient.
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Authors | Bronisława Pietrzak, Pawel Kaminski, Miroslaw Wielgos, Katarzyna Bobrowska, Magdalena Durlik |
Journal | Neuro endocrinology letters
(Neuro Endocrinol Lett)
Vol. 27
Issue 5
Pg. 679-82
(Oct 2006)
ISSN: 0172-780X [Print] Sweden |
PMID | 17159814
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Contraceptives, Oral, Combined
- Ethinyl Estradiol
- Cholesterol
- Creatinine
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Topics |
- Adolescent
- Adult
- Body Mass Index
- Cholesterol
(blood)
- Contraception
(adverse effects)
- Contraceptives, Oral, Combined
(adverse effects)
- Creatinine
(blood)
- Ethinyl Estradiol
(administration & dosage, adverse effects)
- Female
- Follow-Up Studies
- Humans
- Kidney Transplantation
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