[Neurological complications of lymphomas].

Abstract

Peripheral neurological complications of lymphomas are rare, but all types of neuropathy can be observed in the context of lymphoma. This great clinical heterogeneity can be related to the variety of pathological processes that can affect the peripheral nerve or be linked to the different subtypes of lymphoma. In addition to the common causes of peripheral nerve involvement, such as iatrogenic toxicity, there are mechanisms that are more specifically related to lymphomas, such as nerve tumor infiltration, or dysimmune perturbations induced by the hemopathy. These dysimmune processes can result in various neuropathies, such as inflammatory demyelinating polyradiculoneuropathy, or neuropathies secondary to the secretion of a monoclonal immunoglobulin. Identifying the mechanism of the neuropathy is necessary in order to determine the therapeutic options and to improve the prognosis.

• Authors: K Viala
• Journal: Revue neurologique (Rev Neurol (Paris)) Vol. 162 Issue 12 Pg. 1273-8 (Dec 2006) ISSN: 0035-3787 [Print] France
• Vernacular Title: Neuropathies associées aux lymphomes.
• PMID: 17151523 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Antibodies, Monoclonal

Topics

• Antibodies, Monoclonal (analysis)
• Humans
• Inflammation
• Lymphoma (complications, immunology, pathology)
• Motor Neurons (pathology, physiology)
• Peripheral Nervous System Diseases (etiology, immunology, pathology)