Abstract | BACKGROUND: METHODS: Overnight polysomnography was performed on 32 hemodialysis patients (24 men/8 women, 54 +/- 16 years), and on 19 healthy subjects of similar age, sex and body mass index who were used as controls. RESULTS: In hemodialysis patients, the most frequent sleep disorder was SAHS in 44% (14/32), followed by insomnia in 41% (13/32). Compared to healthy controls, patients on hemodialysis showed less slow-wave sleep and rapid eye movement sleep (23 vs. 36%, p = 0.001), less sleep efficiency (71 vs. 87%, p = 0.0079) and a higher periodic limb movement index (39.7 vs. 9.1; p = 0.003). An increase in apnea-hypopnea index (18.9 vs. 4.3; p = 0.007) and dips in the SaO(2) (> or =4%) per hour of sleep (22.6 vs. 6.4; p = 0.021) were also significantly greater in hemodialysis patients than controls. 72% of the cases of SAHS were diagnosed solely by means of polysomnography. CONCLUSIONS: The patients on hemodialysis showed poor sleep quality with a significant increase in the apnea-hypopnea index and in the number of dips in SaO(2). SAHS was underdiagnosed in a large percentage of the hemodialysis patients.
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Authors | B Jurado-Gamez, A Martin-Malo, M A Alvarez-Lara, L Muñoz, A Cosano, P Aljama |
Journal | Nephron. Clinical practice
(Nephron Clin Pract)
Vol. 105
Issue 1
Pg. c35-42
( 2007)
ISSN: 1660-2110 [Electronic] Switzerland |
PMID | 17114901
(Publication Type: Journal Article)
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Copyright | Copyright 2007 S. Karger AG, Basel. |
Topics |
- Causality
- Comorbidity
- Cross-Sectional Studies
- Diagnosis, Differential
- Diagnostic Errors
- Female
- Humans
- Kidney Failure, Chronic
(epidemiology, therapy)
- Male
- Middle Aged
- Polysomnography
- Renal Dialysis
(adverse effects, statistics & numerical data)
- Sleep Apnea Syndromes
(diagnosis, epidemiology)
- Sleep Wake Disorders
(diagnosis, epidemiology, etiology)
- Snoring
(diagnosis, epidemiology)
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