[The use in in vitro reactions of a house dust allergen prepared by a rapid method].

Abstract

The author suggests a method for preparing home dust allergen within 24 hours. Biochemical and trace-element characteristics of raw material for the preparation of this allergen are presented. The resultant allergen was effective in initiation of basophil degranulation test and of leukocytic synthesis of leukotrienes; the leukocytes were isolated from patients (adults and children) suffering from asthma and preasthma. Hypersensitivity diagnosis can be made more accurate if home dust allergen homologous to patient's home, prepared by the rapid method, is used in the studies.

• Authors: O G Ivan'ko
• Journal: Laboratornoe delo (Lab Delo) Issue 3 Pg. 73-5 ( 1991) ISSN: 0023-6748 [Print] Russia (Federation)
• Vernacular Title: Ispol'zovanie v reaktsiiakh in vitro allergena domashneĭ pyli, poluchennogo ékspress-metodom.
• PMID: 1710731 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Dust
• Leukotrienes

Topics

• Adult
• Basophil Degranulation Test
• Child, Preschool
• Dust
• Humans
• In Vitro Techniques
• Leukotrienes (metabolism)
• Male
• Time Factors