Clozapine-induced effuso-constrictive pericarditis. Case report and review of the literature.

Abstract

Clozapine is a widely used antipsychotic medication and is effective against both positive and negative symptoms of schizophrenia. However, clozapine use should be monitored closely due to its side effects profile. The main side effects include cardiorespiratory symptoms, seizures and agranulocytosis. We report a case of effuso-constrictive pericarditis soon after being started on clozapine therapy, whose symptoms improved after discontinuation of clozapine. The literature is reviewed and importance of monitoring is discussed.

• Authors: S Rathore, N D Masani, P O Callaghan
• Journal: Cardiology (Cardiology) Vol. 108 Issue 3 Pg. 183-5 ( 2007) ISSN: 1421-9751 [Electronic] Switzerland
• PMID: 17085936 (Publication Type: Case Reports, Journal Article)
• Copyright: 2007 S. Karger AG, Basel

Chemical References

• Antipsychotic Agents
• Clozapine

Topics

• Antipsychotic Agents (adverse effects, therapeutic use)
• Clozapine (adverse effects, therapeutic use)
• Humans
• Male
• Middle Aged
• Pericarditis, Constrictive (chemically induced)
• Schizophrenia (drug therapy)