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[Use of Permacol in complicated incisional hernia].

Abstract
Polypropylene mesh repair is the gold standard for primary inguinal hernia and incisional hernia. Wound infection and small bowel fistulas are contraindications to polypropylene mesh repair. In addition, synthetic meshes are known to cause severe peritoneal adhesions and enteric fistulas if located close to the bowel. Porcine intestinal submucosa has been used successfully in experimental studies in dogs and rats to repair large abdominal wall defects. A new porcine dermal collagen graft has been used in man for groin hernia repair, incisional hernia repair and other surgical procedures without complications. We describe 6 cases of complicated incisional hernia operated in emergency using porcine dermal collagen grafts. In one woman the incisional hernia was associated with an enterovaginal fistula. Three cases presented severe wound infections, two of which related to a previous polypropylene mesh repair, while another had an irreducible recurrent incisional hernia and one woman presented complete evisceration. None of the patients had postoperative or porcine-graft-related complications. Over a follow-up period of 3-24 months we have had no recurrence or wound infection. The results of these few cases confirm the safety and efficacy of the porcine dermal collagen mesh also in incisional hernia repair.
AuthorsMariano Fortunato Armellino, Guglielmo De Stefano, Francesco Scardi, Anna Lucia Forner, Francesco Ambrosino, Roberto Bellotti, Umberto Robustelli, Giovanni De Stefano
JournalChirurgia italiana (Chir Ital) 2006 Sep-Oct Vol. 58 Issue 5 Pg. 627-30 ISSN: 0009-4773 [Print] Italy
Vernacular TitleL'impiego del Permacol nei laparoceli complicati.
PMID17069192 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Biocompatible Materials
  • Permacol
  • Collagen
Topics
  • Aged
  • Aged, 80 and over
  • Biocompatible Materials (therapeutic use)
  • Collagen (therapeutic use)
  • Female
  • Follow-Up Studies
  • Hernia, Ventral (complications, surgery)
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome

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