[Anesthetic management of a patient with mitochondrial encephalomyopathy under total intravenous anesthesia].

Abstract

This report describes a patient with mitochondrial encephalomyopathy who underwent tracheostomy under total intravenous anesthesia. This 15-year-old girl had been suffering from aspiration pneumonia repeatedly. Anesthesia was induced with propofol (30 mg) and fentanyl (50 microg), and the trachea was intubated without a muscle relaxant. The patient was mechanically ventilated also without a relaxant, and anesthesia was maintained with a continuous infusion of propofol 4-10 mg x kg(-1) x hr(-1) and a bolus injection of fentanyl 25 microg. Bispectral index (BIS) was monitored and maintained at 15-65. The patient showed smooth recovery from anesthesia, and the BIS value returned to the pre-anesthetic level 15 minutes after completion of the anesthesia. Her postoperative course was uneventful. We conclude that total intravenous anesthesia by propofol and fentanyl is a preferable method for the management of the patient with mitochondrial encephalomyopathy.

• Authors: Yumiko Tatsumi, Mashiho Nakashima, Takashi Kitao, Kojiro Kan, Takako Tomita, Yuko Hashimoto, Yoshiaki Ema, Tomotaka Kitagawa, Koichi Oguri, Shuichi Yokota
• Journal: Masui. The Japanese journal of anesthesiology (Masui) Vol. 55 Issue 10 Pg. 1228-30 (Oct 2006) ISSN: 0021-4892 [Print] Japan
• PMID: 17051981 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Propofol

Topics

• Adolescent
• Anesthesia, Intravenous (methods)
• Female
• Humans
• Mitochondrial Encephalomyopathies
• Monitoring, Intraoperative
• Propofol
• Tracheotomy