Update on dermal substitutes.

Abstract

Tissue-engineered biological dressings offer promise in the treatment of burns, chronic ulcers, donor site and other surgical wounds, and a variety of dermatologic conditions. Despite this promise, cellular tissue-engineered products such a Dermagraft and Apligraf have suffered setbacks in recent years with a lower market share than the commercial promoters of these products anticipated. AlloDerm acellular dermal matrix, an older technology than these cell-based products, has made strong progress in winning over clinicians in various disciplines. Similarly, Integra Bilayer Matrix Wound Dressing (BMWD) continues to gain acceptance beyond its original burn audience. A review on the products is offered.

• Authors: Michael Ehrenreich, Zbigniew Ruszczak
• Journal: Acta dermatovenerologica Croatica : ADC (Acta Dermatovenerol Croat) Vol. 14 Issue 3 Pg. 172-87 ( 2006) ISSN: 1330-027X [Print] Croatia
• PMID: 17010268 (Publication Type: Journal Article, Review)

Chemical References

• Alloderm
• integra artificial skin
• Chondroitin Sulfates
• Collagen

Topics

• Chondroitin Sulfates
• Collagen
• Humans
• Skin, Artificial