Liver transplant for metastatic neuroendocrine tumor.

Abstract

Generally, the results of liver transplantation for metastatic liver disease have not been favorable. One exception has been the unique group of neuroendocrine tumors, the slow growth of which allows liver transplantation to effectively palliate and control symptoms. We report two cases: (a) A 51-year-old man who underwent orthotopic liver transplantation and resection of the pancreatic primary tumor for a nonfunctioning malignant neuroendocrine tumor with features of both carcinoid and islet-cell glucagonoma remains symptom-free and without evidence of tumor recurrence at 13 months follow-up. (b) A 47-year-old man who underwent orthotopic liver transplantation and Whipple resection for a metastatic islet-cell tumor in the head of the pancreas is fully recovered at 5 months follow-up.

• Authors: A E Alsina, S Bartus, D Hull, R Rosson, R T Schweizer
• Journal: Journal of clinical gastroenterology (J Clin Gastroenterol) Vol. 12 Issue 5 Pg. 533-7 (Oct 1990) ISSN: 0192-0790 [Print] United States
• PMID: 1699994 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Humans
• Liver Neoplasms (secondary, surgery)
• Liver Transplantation
• Male
• Middle Aged
• Neoplasms, Glandular and Epithelial (secondary, surgery)
• Palliative Care
• Pancreatic Neoplasms (pathology)