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Drug hepatotoxicity.

Abstract
Drug-induced liver injury is a common but underdiagnosed cause of liver disease with an incidence that is rapidly increasing. The authors address some of the more controversial aspects in relation to drug-induced liver injury: recommendations on the use of anti-tuberculosis therapy in the presence of underlying cirrhosis, the role of periodic liver test monitoring and steroid therapy in relation to drug-induced liver injury, the presence of class effects associated with certain drugs, and the potential use of ursodeoxycholic acid in prolonged cholestasis.
AuthorsRahul A Nathwani, Neil Kaplowitz
JournalClinics in liver disease (Clin Liver Dis) Vol. 10 Issue 2 Pg. 207-17, vii (May 2006) ISSN: 1089-3261 [Print] United States
PMID16971258 (Publication Type: Journal Article, Review)
Chemical References
  • Anti-Inflammatory Agents
  • Antitubercular Agents
Topics
  • Anti-Inflammatory Agents (therapeutic use)
  • Antitubercular Agents (therapeutic use)
  • Chemical and Drug Induced Liver Injury
  • Humans
  • Liver Diseases (diagnosis, therapy)
  • Liver Function Tests

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