Abstract |
An inhibition of sex hormone secretion is observed in domestic animals exposed to cadmium in experimental conditions. Ninety-six gilts (Duroc x Landrace x Yorkshire, initial weight 27.59 kg) were randomly assigned into four different groups with three replications in each group (eight gilts per replication). The groups received the corn-soybean basal diet and supplemented with 0, 0.5, 5.0 and 10.0 mg/kg cadmium (as CdCl2) respectively. The feeding trial was ended when body weight of pigs was approximately 90 kg. The results showed that 10.0 mg/kg cadmium significantly decreased average daily gain (p < 0.05) and increased feed/gain ratio (p < 0.05) of pigs. Follicle-stimulating hormone, luteinizing hormone, oestradiol (E2) and progesterone levels in serum of the pigs fed the diet supplemented with 10.0 mg/kg cadmium were lower significantly than those of the control (p < 0.05). Compared with the control, no changes were found in the levels mentioned above when the pigs fed the diet supplemented with 0.5 or 5.0 mg/kg cadmium (p > 0.05). The changes of regulatory mechanism of the pituitary-ovary axis may be the result of cadmium accumulation in pituitary and ovary and should be investigated further.
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Authors | X-Y Han, Z-R Xu, Y-Z Wang, W-L Du |
Journal | Journal of animal physiology and animal nutrition
(J Anim Physiol Anim Nutr (Berl))
Vol. 90
Issue 9-10
Pg. 380-4
(Oct 2006)
ISSN: 0931-2439 [Print] Germany |
PMID | 16958794
(Publication Type: Journal Article)
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Chemical References |
- Cadmium
- Progesterone
- Estradiol
- Luteinizing Hormone
- Follicle Stimulating Hormone
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Topics |
- Animal Feed
- Animal Nutritional Physiological Phenomena
- Animals
- Cadmium
(pharmacology)
- Dose-Response Relationship, Drug
- Estradiol
(blood)
- Female
- Follicle Stimulating Hormone
(blood)
- Luteinizing Hormone
(blood)
- Organ Size
(drug effects)
- Organ Specificity
- Progesterone
(blood)
- Random Allocation
- Swine
(blood, growth & development)
- Weight Gain
(drug effects)
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