Abstract |
Two hundred thirty of 696 evaluable children were identified as having chronic idiopathic thrombocytopenic purpura ( ITP). Splenectomy was performed in 30 (13%), achieving remission in 22 (73%). Favorable response was associated to higher initial platelet count. Spontaneous remission was achieved by 53/200 non-splenectomized patients (26.5%), up to 10 years from diagnosis. More than half of them recovered between 6th and 12th month from diagnosis. The recovery rate was significantly higher (P=0.03) in children aged<9 years (31.2%) than in older children (14.6%). No reliable factor predictive of response in individual cases is still available.
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Authors | Hugo Donato, Armando Picón, María Cristina Rapetti, Amadeo Rosso, Gabriel Schvartzman, Constanza Drozdowski, Juan Jose Di Santo |
Journal | Pediatric blood & cancer
(Pediatr Blood Cancer)
Vol. 47
Issue 5 Suppl
Pg. 737-9
(Oct 15 2006)
ISSN: 1545-5009 [Print] United States |
PMID | 16933257
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright (c) 2006 Wiley-Liss, Inc. |
Topics |
- Adolescent
- Age Factors
- Child
- Child, Preschool
- Chronic Disease
- Databases, Factual
- Follow-Up Studies
- Humans
- Infant
- Outcome Assessment, Health Care
- Platelet Count
- Purpura, Thrombocytopenic, Idiopathic
(diagnosis, surgery)
- Remission Induction
- Remission, Spontaneous
- Splenectomy
- Treatment Outcome
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