These guidelines for the treatment of persons who have
sexually transmitted diseases (
STDs) were developed by CDC after consultation with a group of professionals knowledgeable in the field of
STDs who met in Atlanta, Georgia, during April 19-21, 2005. The information in this report updates the
Sexually Transmitted Diseases Treatment Guidelines, 2002 (MMWR 2002;51[No. RR-6]). Included in these updated guidelines are an expanded diagnostic evaluation for
cervicitis and
trichomoniasis; new antimicrobial recommendations for
trichomoniasis; additional data on the clinical efficacy of
azithromycin for chlamydial
infections in pregnancy; discussion of the role of Mycoplasma genitalium and
trichomoniasis in
urethritis/
cervicitis and treatment-related implications; emergence of
lymphogranuloma venereum protocolitis among men who have sex with men (MSM); expanded discussion of the criteria for spinal fluid examination to evaluate for
neurosyphilis; the emergence of
azithromycin- resistant Treponema pallidum; increasing prevalence of
quinolone-resistant Neisseria gonorrhoeae in MSM; revised discussion concerning the sexual transmission of
hepatitis C; postexposure prophylaxis after sexual assault; and an expanded discussion of STD prevention approaches.