Abstract | UNLABELLED: OBJECTIVE: MATERIALS AND METHODS: Postal survey in 100 neonatal units. RESULTS: Answers were obtained from 81 units. Sixty-three units use systematic prophylactic treatment and the threshold of gestationnal age (weeks gestation) for this systematic treatment is 32 weeks. Caffeine citrate is administered as a loading dose of 20 mg/kg followed by a maintenance dose of 5 mg/kg in 95% of the units. Discontinuing the treatment occurs between 33 and 35 weeks in 37% of the units and between 35 and 37 weeks in 53%. Two third of neonatologits describe recurrent apnea beyond 37 weeks, with the need to continue treatment. Fourteen units sometimes discharge babies at home with ambulatory caffeine citrate treatment and discontinue treatment by 42 to 46 weeks'gestation. A mean duration of 5 days without apnea is required before discharge. CONCLUSION: French teams respect "recommendations" concerning doses and duration without apnea before discharge. Indication of treatment, threshold for systematic treatment, duration of treatment and ambulatory treatment differ among teams.
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Authors | S Ducrocq, V Biran-Mucignat, F Lebas, J-J Baudon, F Gold |
Journal | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
(Arch Pediatr)
Vol. 13
Issue 10
Pg. 1305-8
(Oct 2006)
ISSN: 0929-693X [Print] France |
Vernacular Title | Utilisation du citrate de caféine pour le traitement des apnées idiopathiques du prématuré dans les équipes Françaises de médecine néonatale. |
PMID | 16872813
(Publication Type: Journal Article)
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Chemical References |
- Central Nervous System Stimulants
- Citrates
- Caffeine
- caffeine citrate
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Topics |
- Apnea
(drug therapy)
- Caffeine
(therapeutic use)
- Central Nervous System Stimulants
(therapeutic use)
- Citrates
(therapeutic use)
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Drug Utilization
(statistics & numerical data)
- France
- Humans
- Infant, Newborn
- Infant, Premature
- Infant, Premature, Diseases
(drug therapy)
- Intensive Care Units, Neonatal
- Surveys and Questionnaires
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