Prescription of medroxyprogesterone acetate to a patient with pedophilia, resulting in Cushing's syndrome and adrenal insufficiency.

Abstract

This article provides a case report of a patient with pedophilia who was treated over a 4-year period with medroxyprogesterone acetate (MPA) at a dose of 300 mg/day and as a consequence developed Cushing's Syndrome and adrenal insufficiency, for which he was treated and from which he recovered. He also reported a hypersexual reaction to his own past cessation of MPA. Gonadotropin-releasing hormone agonists, which have a more benign side-effect profile than MPA, are suggested as an alternative to MPA.

• Authors: Richard B Krueger, Wylie Hembree, Michael Hill
• Journal: Sexual abuse : a journal of research and treatment (Sex Abuse) Vol. 18 Issue 2 Pg. 227-8 (Apr 2006) ISSN: 1079-0632 [Print] United States
• PMID: 16868842 (Publication Type: Journal Article)

Chemical References

• Contraceptive Agents, Male
• Medroxyprogesterone Acetate

Topics

• Adrenal Insufficiency (chemically induced)
• Adult
• Aggression (drug effects)
• Contraceptive Agents, Male (adverse effects)
• Cushing Syndrome (chemically induced)
• Humans
• Male
• Medroxyprogesterone Acetate (adverse effects)
• Pedophilia (drug therapy, prevention & control)
• Pituitary-Adrenal System (drug effects)