Erythrokeratodermia variabilis with adult onset: report of a sporadic case unresponsive to systemic retinoids.

Abstract

Erythrokeratodermia variabilis is a rare autosomal-dominant genodermatosis characterized by migratory and erythematous patches changing over the course of hours to days, and fixed keratotic plaques. The disease begins mostly at birth or within the first year of life; it very rarely starts after childhood. We present herein a sporadic case with adult onset that was unusually resistant to both isotretinoin and acitretin.

• Authors: Zülal Erbagci, Almila A Tuncel, Hale Deniz
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 17 Issue 3 Pg. 187-9 ( 2006) ISSN: 0954-6634 [Print] England
• PMID: 16854764 (Publication Type: Case Reports, Journal Article)

Chemical References

• Keratolytic Agents
• Isotretinoin
• Acitretin

Topics

• Acitretin (administration & dosage, therapeutic use)
• Administration, Oral
• Adult
• Diagnosis, Differential
• Female
• Humans
• Hyperkeratosis, Epidermolytic (diagnosis, drug therapy, pathology)
• Isotretinoin (administration & dosage, therapeutic use)
• Keratolytic Agents (administration & dosage, therapeutic use)
• Skin Diseases, Genetic (diagnosis, drug therapy, pathology)
• Treatment Failure