HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Anterior thoracic spine reconstruction using a titanium mesh cage and pedicled rib flap.

AbstractSTUDY DESIGN:
A retrospective clinical study.
OBJECTIVES:
To evaluate the safety and efficacy of using an integrated titanium mesh cage and pedicled rib flap for thoracic spine reconstruction in patients at high risk of pseudarthrosis.
SUMMARY OF BACKGROUND DATA:
A variety of materials are available for interbody thoracic reconstruction; however, the optimal treatment of patients at high risk of pseudarthrosis remains a challenging problem. Free or pedicled bone flaps have been shown to be highly effective in terms of promoting fusion and titanium mesh cages provide excellent structural support.
METHODS:
Eleven patients who underwent anterior thoracic corpectomy and spinal reconstruction using an integrated titanium mesh cage and pedicled rib flap were analyzed with a mean follow-up of 37 months (range, 25-55 months). The etiology of spinal disease was infection in 7 (64%) patients and tumor in the remaining 4 (36%) patients. Seven (64%) patients were treated with only an anterior approach while the remaining 4 (36%) patients underwent circumferential spinal reconstruction.
RESULTS:
All patients demonstrated clinical and radiographic evidence of spinal fusion at the time of follow-up. All patients had stable or improved Frankel grades after surgery. There was a mean kyphosis correction of 7 degrees for both the focal and regional thoracic kyphosis. There were three significant postoperative complications: bilateral pleural effusion, gram-negative bacteremia, and transient right lower extremity weakness requiring reoperation and pedicle screw revision. Two patients died after surgery: one from aneurysmal subarachnoid hemorrhage and the other from complications of breast cancer.
CONCLUSIONS:
The use of an integrated rib flap and titanium mesh cage construct appears to be a safe and effective means of providing immediate and substantial anterior column support as well as achieving arthrodesis in challenging fusion candidates.
AuthorsBrian A O'Shaughnessy, Stephen L Ondra, Aruna Ganju, Hakim K Said, Julius W Few, John C Liu
JournalSpine (Spine (Phila Pa 1976)) Vol. 31 Issue 16 Pg. 1820-7 (Jul 15 2006) ISSN: 1528-1159 [Electronic] United States
PMID16845358 (Publication Type: Journal Article)
Chemical References
  • Titanium
Topics
  • Adult
  • Aged
  • Bacteremia (etiology)
  • Bacterial Infections (complications)
  • Female
  • Gram-Negative Bacterial Infections (etiology)
  • Humans
  • Internal Fixators
  • Male
  • Middle Aged
  • Nervous System Diseases (etiology)
  • Pleural Effusion (etiology)
  • Radiography
  • Retrospective Studies
  • Ribs
  • Spinal Diseases (etiology, surgery)
  • Spinal Fusion (adverse effects)
  • Spinal Neoplasms (surgery)
  • Surgical Flaps
  • Thoracic Vertebrae (diagnostic imaging, surgery)
  • Titanium
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: