[Prognostic value of headache in cardioembolic stroke].

To characterize the clinical features, prognosis and clinical predictors of headache in cardioembolic stroke (CS).
Descriptive study of 480 patients with CS included in the Sagrat Cor Hospital of Barcelona Stroke Registry over a 17 year period. The vascular risk factors, clinical profiles and topographic data in CS with and without headache were compared. The independent predictive value of each variable on the development of headache in CS was assessed with a logistic regression analysis.
Headache was diagnosed in 38 of 480 patients (7.9%) with CS Early neurologic deterioration was present in 40 patients (8.3%), and was significantly more frequent in patients with than without headache (17.5% vs 7%; p < 0.03). The presence of early neurologic deterioration was a significant predictive variable associated with headache in CS in the 2 logistic regression models (odds ratio [OR] = 3.34, and OR = 3.36). Other clinical variables were: cranial nerve palsy (OR = 7.54; 95% confidence interval [CI], 1.98-28.70), ataxia (OR = 4.88; 95% CI, 1.65-14.50), ischemic heart disease (OR = 3.02; 95% CI, 1.41-6.45), hyperlipidemia (OR = 2.61; 95% CI, 1.08-6.28), age (OR = 0.96; 95% CI, 0.93-0.99), and sudden onset (OR = 0.43; 95% CI, 0.21-0.91). Topographic profile were: posteroinferocerebellar artery involvement (OR = 21.41; 95% CI, 3.10-148.04), basilar artery involvement (OR = 9.04; 95% CI, 1.87-43.66) and cerebral posterior involvement (OR = 6.12; 95% CI, 2.30-16.29).
Headache in CS is more frequent in vertebrobasilar involvement. Headache is related with early neurological deterioration and associated with increased morbidity and mortality.
AuthorsAdrià Arboix
JournalMedicina clínica (Med Clin (Barc)) Vol. 127 Issue 1 Pg. 5-7 (Jun 3 2006) ISSN: 0025-7753 [Print] Spain
Vernacular TitleValor pronóstico de la cefalea en el infarto cerebral cardioembólico.
PMID16796932 (Publication Type: English Abstract, Journal Article)
  • Aged
  • Female
  • Headache (epidemiology)
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Stroke (physiopathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: