Carbon dioxide laser microsurgery for early glottic carcinoma.

Abstract

OBJECTIVES:

To define the oncologic efficacy of transoral endoscopic CO2 laser surgery in early glottic carcinoma.

METHODS:

A retrospective study of 103 patients with glottic carcinoma (14 Tis, 68 pT1a, 14 pT1b, and 7 pT2) treated from October 1993 to June 2001. Surgical treatment included endoscopic CO2 laser cordectomies according to the classification of the European Laryngological Society.

RESULTS:

According to the Kaplan-Meier method, the probability of remaining free of local recurrence 5 years after primary surgery alone was 100% for the Tis, 96.05% for the T1, and 100% for the T2. Local control at 5 years after exclusive CO2 laser salvage surgery was 98.03%. The probability of remaining free of local recurrence 5 years after any type of salvage surgery was 100%. Laryngeal preservation was achieved in 100% of the cases.

CONCLUSIONS:

According to the present series, endoscopic CO2 laser surgery is an effective treatment for early glottic cancer.

EBM RATING:

C-4.

• Authors: Gian Peppino Ledda, Roberto Puxeddu
• Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (Otolaryngol Head Neck Surg) Vol. 134 Issue 6 Pg. 911-5 (Jun 2006) ISSN: 0194-5998 [Print] England
• PMID: 16730529 (Publication Type: Evaluation Study, Journal Article)

Chemical References

• Carbon Dioxide

Topics

• Adult
• Aged
• Aged, 80 and over
• Carbon Dioxide
• Carcinoma, Squamous Cell (classification, surgery)
• Disease-Free Survival
• Female
• Glottis (parasitology)
• Humans
• Laryngeal Neoplasms (classification, surgery)
• Laser Therapy (methods)
• Male
• Microsurgery (methods)
• Middle Aged
• Neoplasm Recurrence, Local (prevention & control)
• Retrospective Studies
• Treatment Outcome