Abstract | BACKGROUND: METHOD: Two motor vehicle accident patients and one near drowning patient, all of them in the permanent vegetative state for at least three years, were rated according to the Glasgow Coma and Rancho Los Amigos scale before and after zolpidem application. Long term response to daily application of this drug was monitored for 3-6 years. RESULTS: All patients were aroused transiently every morning after zolpidem. Glasgow Coma Scale scores ranged from 6-9/15 before to 10-15/15 after zolpidem. Rancho Los Amigos Cognitive scores ranged from I-II before to V-VII afterward. Drug efficacy did not decrease and there were no long term side effects after 3-6 years daily use. CONCLUSION:
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Authors | Ralf Clauss, Wally Nel |
Journal | NeuroRehabilitation
(NeuroRehabilitation)
Vol. 21
Issue 1
Pg. 23-8
( 2006)
ISSN: 1053-8135 [Print] Netherlands |
PMID | 16720934
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- GABA Agonists
- Pyridines
- Zolpidem
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Topics |
- Adult
- Arousal
(drug effects)
- Drug Administration Schedule
- Follow-Up Studies
- GABA Agonists
(administration & dosage)
- Glasgow Coma Scale
- Humans
- Male
- Persistent Vegetative State
(drug therapy, physiopathology, psychology)
- Pyridines
(administration & dosage)
- Zolpidem
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