Endoscopic band ligation therapy for upper gastrointestinal bleeding related to Mallory-Weiss syndrome.

Abstract

BACKGROUND:

No consensus exists as to the best endoscopic treatment for Mallory-Weiss syndrome. Endoscopic band ligation is a readily available and easily learned technique. This prospective study evaluated the efficacy and safety of endoscopic band ligation therapy for Mallory-Weiss syndrome.

METHODS:

From August 1998 to June 2005, a clinical trial assessed 37 patients with a diagnosis of Mallory-Weiss syndrome who had active bleeding, exposed vessels, or both. Their lesions were treated using endoscopic band ligation.

RESULTS:

Endoscopic band ligation was successful in 36 of 37 cases, with a follow-up period ranging from 1 to 24 months. The remaining patient had severe liver failure and disseminated intravascular coagulation. The patient bled again at 12 h and subsequently died. Except for this case, no recurrent bleeding, perforation, or other complications occurred.

CONCLUSIONS:

The study results suggest that endoscopic band ligation is an effective, safe, and easily learned procedure for treating upper gastrointestinal bleeding related to Mallory-Weiss syndrome.

• Authors: N Higuchi, K Akahoshi, Y Sumida, M Kubokawa, Y Motomura, M Kimura, M Matsumoto, K Nakamura, H Nawata
• Journal: Surgical endoscopy (Surg Endosc) Vol. 20 Issue 9 Pg. 1431-4 (Sep 2006) ISSN: 1432-2218 [Electronic] Germany
• PMID: 16703428 (Publication Type: Journal Article)

Topics

• Adult
• Aged
• Aged, 80 and over
• Disseminated Intravascular Coagulation (complications)
• Endoscopy, Gastrointestinal (adverse effects)
• Female
• Follow-Up Studies
• Gastrointestinal Hemorrhage (etiology, mortality, surgery)
• Humans
• Ligation (adverse effects, methods)
• Liver Failure (complications)
• Male
• Mallory-Weiss Syndrome (complications)
• Middle Aged
• Prospective Studies
• Recurrence
• Treatment Outcome