Abstract | BACKGROUND: METHODS: H1RKO and wild-type mice were sensitized by intraperitoneal injection of ovalbumin (OVA) or saline, and then challenged with aerosolized OVA or saline. Ventilatory timing in response to inhaled methacholine was measured, and samples of blood, bronchoalveolar lavage, and lung tissues were taken 24 h after the last OVA challenge. RESULTS: CONCLUSION:
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Authors | Kenichi Miyamoto, Michiko Iwase, Miki Nyui, Satoru Arata, Yasushi Sakai, Esteban C Gabazza, Hiroshi Kimura, Ikuo Homma |
Journal | International archives of allergy and immunology
(Int Arch Allergy Immunol)
Vol. 140
Issue 3
Pg. 215-22
( 2006)
ISSN: 1018-2438 [Print] Switzerland |
PMID | 16685135
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cytokines
- Receptors, Histamine H1
- Methacholine Chloride
- Immunoglobulin E
- Ovalbumin
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Topics |
- Animals
- Asthma
(immunology)
- Bronchial Provocation Tests
- Bronchoalveolar Lavage Fluid
(chemistry, cytology)
- Cytokines
(analysis)
- Disease Models, Animal
- Enzyme-Linked Immunosorbent Assay
- Histocytochemistry
- Hypersensitivity
(immunology)
- Immunoglobulin E
(blood)
- Lung
(immunology)
- Male
- Methacholine Chloride
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Ovalbumin
(immunology)
- Receptors, Histamine H1
(deficiency, immunology)
- Specific Pathogen-Free Organisms
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