Abstract |
The purpose of this study was to evaluate the effect of lethal photosensitization and guided bone regeneration (GBR) on the treatment of ligature-induced peri-implantitis in different implant surfaces. The treatment outcome was evaluated by clinical and histometric methods. A total of 40 dental implants with four different surface coatings (10 commercially pure titanium surface (cpTi); 10 titanium plasma-sprayed (TPS); 10 acid-etched surface; 10 surface- oxide sandblasted) were inserted into five mongrel dogs. After 3 months, the animals with ligature-induced peri-implantitis were subjected to surgical treatment using a split-mouth design. The controls were treated by debridment and GBR, while the test side received an additional therapy with photosensitization, using a GaAlAs diode laser, with a wavelength of 830 nm and a power output of 50 mW for 80 s (4 J/cm2), and sensitized toluidine blue O (100 microg/ml). The animals were sacrificed 5 months after therapy. The control sites presented an earlier exposition of the membranes on all coating surfaces, while the test group presented a higher bone height gain. Re-osseointegration ranged between 41.9% for the cpTi surface and 31.19% for the TPS surface in the test sites; however differences were not achieved between the surfaces. The lethal photosensitization associated with GBR allowed for better re-osseointegration at the area adjacent to the peri-implant defect regardless of the implant surface.
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Authors | Jamil Awad Shibli, Marilia Compagnoni Martins, Fernando Salimon Ribeiro, Valdir Gouveia Garcia, Francisco Humberto Nociti Jr, Elcio Marcantonio Jr |
Journal | Clinical oral implants research
(Clin Oral Implants Res)
Vol. 17
Issue 3
Pg. 273-81
(Jun 2006)
ISSN: 0905-7161 [Print] Denmark |
PMID | 16672022
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Coated Materials, Biocompatible
- Dental Implants
- Dental Materials
- Photosensitizing Agents
- Tolonium Chloride
- Titanium
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Topics |
- Acid Etching, Dental
- Air Abrasion, Dental
- Animals
- Bone Regeneration
(physiology)
- Coated Materials, Biocompatible
(chemistry)
- Debridement
- Dental Implants
- Dental Materials
(chemistry)
- Dental Prosthesis Design
- Dogs
- Guided Tissue Regeneration, Periodontal
(methods)
- Laser Therapy
- Male
- Mandible
(pathology, surgery)
- Osseointegration
(physiology)
- Periodontitis
(drug therapy, pathology, surgery)
- Photochemotherapy
- Photosensitizing Agents
(therapeutic use)
- Random Allocation
- Surface Properties
- Titanium
(chemistry)
- Tolonium Chloride
(therapeutic use)
- Treatment Outcome
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