Abstract |
We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.
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Authors | Erika Driver-Dunckley, Virgilio Gerald H Evidente, Charles H Adler, Renee Hillman, Jose Hernandez, Geoffrey Fletcher, Mark K Lyons |
Journal | Movement disorders : official journal of the Movement Disorder Society
(Mov Disord)
Vol. 21
Issue 8
Pg. 1287-9
(Aug 2006)
ISSN: 0885-3185 [Print] United States |
PMID | 16671093
(Publication Type: Journal Article)
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Copyright | (c) 2006 Movement Disorder Society |
Chemical References |
- Antiparkinson Agents
- Levodopa
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Topics |
- Aged
- Antiparkinson Agents
(therapeutic use)
- Deep Brain Stimulation
- Female
- Humans
- Levodopa
(therapeutic use)
- Male
- Middle Aged
- Parkinson Disease
(drug therapy, therapy)
- Restless Legs Syndrome
(etiology, therapy)
- Thalamus
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