[Intermittent intravenous immunoglobulin infusion prevented relapses in patients with remission-exacerbation type chronic inflammatory demyelinating polyradiculoneuropathy].

Abstract

The intravenous immunoglobulin infusion therapy (IVIg) has recently acquired an important role in the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Some patients, however, require repetitive infusions to maintain the improvement. We planned a one-day therapy with 0.4 g/kg of IVIg in every 7 or 10 days for two CIDP patients who had required a 5-day course of IVIg in every month because of frequent exacerbations. Serum levels of IgG in both patients were kept as high as 2,000 mg/dl resulting in maintaining the improvement without any side effects.

• Authors: Fumio Kanda, Kenji Sekiguchi, Kenichi Oishi, Hirotoshi Hamaguchi, Shigeru Mitsui, Hiroshi Kobessho, Masatsugu Higuchi, Toshihiko Shirafuji, Hiroyuki Ishihara
• Journal: Rinsho shinkeigaku = Clinical neurology (Rinsho Shinkeigaku) Vol. 46 Issue 3 Pg. 236-8 (Mar 2006) ISSN: 0009-918X [Print] Japan
• PMID: 16642939 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Drug Administration Schedule
• Humans
• Immunoglobulins, Intravenous (administration & dosage)
• Infusions, Intravenous
• Male
• Middle Aged
• Polyradiculoneuropathy, Chronic Inflammatory Demyelinating (therapy)
• Secondary Prevention