Levodopa-responsive parkinsonism associated with hydrocephalus.

Abstract	We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus.
Authors	Mi Jung Kim, Sun J Chung, Young H Sung, Myoung C Lee, Joo-Hyuk Im
Journal	Movement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 21 Issue 8 Pg. 1279-81 (Aug 2006) ISSN: 0885-3185 [Print] United States
PMID	16639728 (Publication Type: Case Reports, Journal Article)
Copyright	(c) 2006 Movement Disorder Society
Chemical References	Antiparkinson Agents Levodopa
Topics	Antiparkinson Agents (therapeutic use) Brain (pathology) Female Humans Hydrocephalus (complications) Levodopa (therapeutic use) Magnetic Resonance Imaging Middle Aged Parkinson Disease (complications, drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!