Abstract | BACKGROUND: METHODS: RESULTS: CONCLUSION: This study provides evidence that antigens prepared from genotypically distinct strains of L. braziliensis induce different degrees of immune response. It also indicates that both parasite and host play a role in the outcome of L. braziliensis infection.
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Authors | Paulo T G Leopoldo, Paulo R L Machado, Roque P Almeida, Albert Schriefer, Angela Giudice, Amélia Ribeiro de Jesus, John L Ho, Luiz Henrique Guimarães, Olívia Bacellar, Edgar M Carvalho |
Journal | BMC infectious diseases
(BMC Infect Dis)
Vol. 6
Pg. 75
(Apr 25 2006)
ISSN: 1471-2334 [Electronic] England |
PMID | 16638143
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antigens, Protozoan
- Cytokines
- Interleukin-5
- Tumor Necrosis Factor-alpha
- Interleukin-10
- Interferon-gamma
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Topics |
- Adolescent
- Adult
- Animals
- Antigens, Protozoan
(immunology, pharmacology)
- Cells, Cultured
- Child
- Cytokines
(biosynthesis, drug effects, immunology)
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Regulation
- Humans
- Interferon-gamma
(analysis, biosynthesis)
- Interleukin-10
(analysis, biosynthesis)
- Interleukin-5
(analysis, biosynthesis)
- Leishmania braziliensis
(immunology)
- Leishmaniasis, Cutaneous
(immunology, parasitology)
- Leishmaniasis, Diffuse Cutaneous
(immunology, parasitology)
- Leukocytes, Mononuclear
(drug effects, immunology)
- Middle Aged
- Tumor Necrosis Factor-alpha
(analysis, biosynthesis)
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