The clinical impact of high frequency ventilation: review of the Cochrane meta-analyses.

Abstract

Experimental work in animal models suggests that ventilation strategies using high frequency oscillatory ventilation or high frequency jet ventilation hold great promise in the prevention of lung injury in preterm infants. However, clinical trials of either modality demonstrate little clinical benefit and there are possibilities of adverse effects, including increased risk of intraventricular hemorrhage and poor neurological development.

• Authors: R F Soll
• Journal: Journal of perinatology : official journal of the California Perinatal Association (J Perinatol) Vol. 26 Suppl 1 Pg. S38-42; discussion S43-5 (May 2006) ISSN: 0743-8346 [Print] United States
• PMID: 16625224 (Publication Type: Journal Article, Meta-Analysis, Review)

Topics

• Bronchopulmonary Dysplasia (therapy)
• Cerebral Hemorrhage (etiology)
• Chronic Disease
• High-Frequency Ventilation (adverse effects)
• Humans
• Infant Mortality
• Infant, Newborn
• Randomized Controlled Trials as Topic
• Respiratory Distress Syndrome, Newborn (therapy)