How we do it: surgery should be considered equally with I131 and thionamide treatment as first-line therapy for thyrotoxicosis.

Abstract

Radioiodine and thionamide treatment are the most frequently used treatment modalities for thyrotoxicosis in Europe and North America with surgery being reserved for selected cases. * In our clinic patients were offered all three modalities via simultaneous interview with an endocrinologist and a surgeon, with international risk benefit data for radioiodine and thionamide therapy, and local risk benefit data for total thyroidectomy provided. * When given the choice, at least 15% of patients opted for total thyroidectomy over the other modalities. * In our series of 100 consecutive surgical patients there was a 4% malignancy rate. * Total thyroidectomy should be offered equally, with radioiodine and thionamide treatment, as a first line treatment modality in the management of thyrotoxicosis.

• Authors: R J A England, M B Kamath, A Jabreel, G Dunne, S L Atkin
• Journal: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (Clin Otolaryngol) Vol. 31 Issue 2 Pg. 160-2 (Apr 2006) ISSN: 1749-4478 [Print] England
• PMID: 16620341 (Publication Type: Journal Article)

Chemical References

• Antithyroid Agents
• Iodine Radioisotopes

Topics

• Adolescent
• Adult
• Aged
• Antithyroid Agents (therapeutic use)
• Female
• Humans
• Iodine Radioisotopes (therapeutic use)
• Male
• Middle Aged
• Thyroidectomy
• Thyrotoxicosis (surgery, therapy)
• Treatment Outcome